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  • This handout provides a brief overview of the most common evidence-based modalities used in veterinary medicine. Pet owners need to discuss the risk of recommended modalities for their specific pet with a trained and certified rehabilitation therapist before starting a rehabilitation program.

  • Ropinirole ophthalmic (Clevor®) is the first FDA-approved drug for inducing vomiting in dogs. Your veterinarian may prescribe this drug off label to use for your dog at home. Ropinirole ophthalmic comes as a single-use dropper for use in the eye.

  • SAMe or S-adenosyl-methionine + Silybin (brand name: Denamarin®) is a combination supplement commonly used to support liver health in cats and dogs. The body uses SAMe for many important functions, such as brain, heart, hormone, antioxidant, detoxifying, and other metabolic functions. The combination of SAMe and Silybin is used to support liver and brain health. This article discusses side effects, interactions, monitoring, and storage.

  • Salicylic acid topical (brand name Solva-Ker®, BioSeb®, Cerasoothe® SA, others) is an antimicrobial and antipruritic (anti-itching) agent used in the treatment of seborrheic (dry or greasy dandruff) disorders in cats, dogs, and other animals. It may be specially compounded and/or combined into a formulation with other medications. It comes in cream, gel, ointment, and shampoo forms.

  • Seboliance (brand name Douxo®S3 SEB) is a natural extract from the pomegranate plant (Punica granatum) used to help control dandruff, reduce odor, and help hydrate dry skin in cats and dogs. Seboliance may be part of a combination product containing ophytrium. Seboliance comes in mousse and shampoo forms.

  • Ophthalmic autologous serum is a blood-derived product used to treat corneal ulcers in animals. Ophthalmic autologous serum is part of the blood and is collected directly from the patient. It is in liquid form.

  • Silver sulfadiazine topical is an antimicrobial used to treat skin infections and burns in cats, dogs, and exotic pets. It is used off label in veterinary medicine. Silver sulfadiazine topical comes in a topical cream.

  • Sodium chloride (hypertonic) ophthalmic is a topical medication used to reduce surface (corneal) swelling of the eye in cats and dogs. Sodium chloride is available without a prescription but should only be used under the direction of a veterinarian. It may be used “off label” or “extra label” to treat eye conditions in animals other than cats or dogs. Sodium chloride (hypertonic) ophthalmic comes in ointment and liquid drop form. Avoid use in animals with corneal ulceration or dry eye.

  • Spinosad (brand name Comfortis®) is an antiparasitic used to kill adult fleas and to prevent and treat flea infestations in dogs and cats. It may be used off label (extra label) to treat other parasites and in other animals. It comes in an oral tablet form.

  • Spironolactone + benazepril (brand name Cardalis®) is a combination aldosterone antagonist (spironolactone) and angiotensin-converting enzyme inhibitor or ACE inhibitor (benazepril) used to treat certain types of congestive heart failure in dogs. Use to treat other heart conditions or in other species is "off label" or "extra label". Spironolactone + benazepril comes in chewable meat-flavored tablet form.